Malaysian Bee Venom Abrogates Carrageenan Induced Inflammation in Rats
Mohd Nuruddin Abd Manap, Onn Haji Hashim and Kamaruddin Mohd Yusoff
This study was carried out to test the hypothesis that Malaysian bee venom (MBV) has the potential to produce a potent anti-inflammatory effect. MBV was obtained by electrical stimulation technique without causing death to the bees. An animal model with carrageenan (CR) induced inflammation was employed and paw volume was measured at each specific time point during the period of this study. Our findings demonstrate that MBV has an anti-inflammatory effect on 1% CR induced inflammation in the rat paw, making it potentially useful in the development of future anti-inflammatory therapies.
Malaysian bee venom, anti-inflammation, carrageenan, rat